Nylon tips clean between teeth while rubber massagers reduce plaque and tartar; made with natural peanut flavor.IngredientsGlycerin,Calcium Carbonate, Water, Hydrated Silica, Sodium Bicarbonate , Sodium Ascorbyl Phosphate, Sodium Copper Chlorophyllin, Sodium Hexametaphosphate, Xanthan Gum, and Natural Flavor. Toothbrush: Nylon and RubberHow to Use: Begin by letting your dog taste a small amount of Nylabone Dental Toothpaste. Using your finger, gently rub teeth and gums in a circular motion. Then introduce the toothbrush with a small amount of toothpaste. Allow your dog to taste, then gently start brushing with a back & forth motion (no rinsing is necessary). Remember to praise and reward with a treat after every successful brushing!